Tuesday, January 8, 2008

13 - biochemistry mcqs - 98 TO 107 - glycolysis

98 - Thiamine pyrophosphate , functions as an ________ sink that acts to stabilize the carbon ion adduct formed during the decarboxylation of pyruvate .

answer is electron sink .

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99 - phosphoglycerate kinase converts 1 , 3 bisphosphoglycerate to 3 phosphoglycerate and forms an ATP .

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100 - the irreversible rate determining step in glycolysis is catalysed by ?

answer is PFK .

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101 - pentose phosphate pathway is also called hexose monophosphate shunt .

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102 - the molecule which conserves the free energy of metabolite oxidation for ATP synthesis ?

NADH .

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103 - The molecule which conserves the free energy of metabolite oxidation for reductive biosynthesis ?

NADPH .

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104 - 6 phosphogluconolactonase ------- 6 - phosphogluconate

6 phosphogluconate dehydrogenase ------------ RU5P

glucose 6 phosphate dehdrogenase -------- first committed step in HMP pathway

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105 - The process of fermentation has greater thermodynamic efficacy under physiological conditions than under standard biochemical conditions ?

the above statement is true .

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106 - under aerobic conditions glucose is oxidised during glycolysis and the coenzyme _________ is reduced and subsequently oxidised in a process known as electron transport ?

NAD +

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107 - in muscle a 10 % decrease in ATP concentration , results in a 100 % increase in ADP concentration and 400 % increase in AMP concentration .

true .


TO READ COMPLETELY ABOUT GLYCOLYSIS CLICK HERE

TO KNOW MORE ABOUT HMP SHUNT CLICK HERE

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12 - biochemistry mcqs - 87 to 97 - glycolysis

87 - lactose build up in the muscle during vigorous activity causes muscle fatigue and soreness .

the above statement is false . it is glycolytically generated acid that causes muscle fatigue and soreness .

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88 - when NADPH is needed from the pentose phosphate pathway , excess ________ is converted to glycolytic intermediates by a sequence of reactions which can operate in reverse .

ribulose - 5 - phosphate .

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89 - which state of PFK , does AMP preferentially bind ?

a- to the R state
b- to the T state
c- to both states without any preference
d- to neither

answer is a . to the R state .

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90 - yeast alcohol dehydrogenase and mammalian liver alcohol dehydrogenase , both require ____

a- Mg + 2
b- Zn + 2
c- calcium
d- iron

answer is b . ZINC .

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91 - glyceraldehyde 3 phosphate is phosphorylated to produce 1 , 3 bisphosphoglycerate to produce one molecule of NADH in the presence of the enzyme GA3P dehydrogenase .

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92 - alcoholic fermentation results in the regenration of NAD + along with the conversion of pyruvate to _______ and CO2 .

answer is ethanol.

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93 - the deficiency of which vitamine results in a condition called beri beri ?

thiamine is the answer .

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94 - transketolase has a thiamine pyrophosphate cofactor and catalyses the transfer of a c2 unit from XU5P to R5P .

true .

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95 - the three products of glycolysis are ATP , NADH and pyruvate .

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96 - what does ATP do to PFK , at high concentrations?

- it acts as an allosteric inhibitor , by binding to the T state .

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97 - the level of available ______, regulates hemoglobin's oxygen affinity ?

answer is 2 ,3 BPG.


TO READ COMPLETELY ABOUT GLYCOLYSIS CLICK HERE

TO KNOW MORE ABOUT HMP SHUNT CLICK HERE

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