21 - the enzyme of the citric acid cycle that is inhibited by NADH ?
Answer is citrate synthase .
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22 - which citric acid cycle intermediates can be used for the synthesis of amino acids and can be regenerated by the same amino acids ?
a- succinyl co A and succinate
b- succinate and fumarate
c- malate and oxaloacetate
d- alpha ketogluatarate and oxaloacetate .
the correct answer is d . alpha ketoglutarate and oxaloacetate .
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23 - what is formed in a second concerted acid - base catalysed step of citrate synthase , in which the acetyl co A enol attacks oxaloacetate ?
answer is citryl co A .
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24 - which is the thiamine pyro phosphate requiring enzyme that decarboxylates pyruvate with the formation of a hydroxyethyl - TPP intermediate ?
answer is pyruvate dehydrogenase .
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25 - what is the name of the catalytically inactive E2 like protein existing in six copies that may help bind E3 to the complex .
answer is PROTEIN X .
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26 - What is the name of the cofactor that is bound to E3 and is reduced by lipoamide?
answer is FAD.
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27 - this cofactor accepts the acetyl group from the lipoamide in the pyruvate dehydrogenase complex ?
answer is coenzyme A .
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28 - This reaction is catalysed by E 3 , in which an acetyl group is transfered to co A , yielding acetyl co A and dihydrolipoamide E2 .
answer is TRANSESTERIFICATION .
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29 - Oxaloacetate undergoes transamination with alanine to produce what ?
a- glutamate and pyruvate
b- glutamate and alpha keto glutarate
c- aspartate and pyruvate
d- aspartate and alpha ketoglutarate
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30 - which enzyme produces the second CO 2 and NADH of the citric acid cycle ?
answer is alpha ketoglutarate dehydrogenase .
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