question : cytochrome oxidase is inhibited by :
a- cyanide
b- aluminium phosphide
c- phenobarbitone
d- carbonmonoxide
e- NO
answer : cyanide and carbon monoxide are the answers .
inhibitors of cytochrome ( a + a3 ) oxidase ( complex IV ) of electron transport chain ( ETC ) are :
1. carbonmonoxide ( inhibits the enzyme by combining with O2 binding sites )
2. cyanide
3. azide ( sodium azide example )
4. H2S
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